Use Nisim NewHair Biofactors so you can . . .

Look In The Mirror Each Morning Without Dreading The Sight Of Your Hair Falling Out!

Nisim NewHair Biofactors products are all natural herbal based products developed using the proprietary extraction methods developed by Nisim after over 20 years of research on the study of hair growth. NewHair Biofactors stops your hair loss or you get your money back - it's that simple!

This is good news for the many people who suffer from hair loss or thinning hair. Although when most people think of hair loss they think of Male Pattern Baldness, many women lose hair as well. In fact almost as many women lose hair as men. Even children can lose hair due to a condition called Alopecia Areata.

Nisim NewHair Biofactors Ultra Deep Scalp Cleansing Shampoo

The shampoo is so effective at controlling hair loss Nisim International states: "Your hair loss will be controlled within a week or your money back."

These unique, ultra deep cleansing shampoos have been specially formulated to maximize a clean and nutrient rich environment for healthy hair growth. The wonderful feeling you get from knowing your scalp is healthy and clean is reason enough to use this shampoo alone.

Use the shampoo as your first step in the advanced NewHair Biofactors system which stops hair loss within 1 week! Nisim shampoos are stand alone products.

Available for both Normal to Oily and Normal to Dry hair in in 8 oz and 33 oz sizes.

Highly Effective Hair Stimulating Extract

The most important step in returning your hair to its original state is the application of the highly effective natural herbal extract.

The extract is designed to maximize the natural growth cycle of your hair. It couldn't be easier. For best results you simply massage the extract into your scalp twice a day.

You will see visible results in three to six months.

The extract is available in two unique formulas. The original formula is for those with oily hair and scalp; and the gel formation, with hyaluronic acid and beta glucan, is ideal for those with dry hair and scalp.

Watch the Nisim NewHair Biofactors Video:

Answers To Frequently Asked Questions

What is the major cause of hair loss in men and women?

Both men and women lose hair for similar reasons.

Men usually lose hair first in the temporal area, second in the crown, and third, in the vertex or top of the scalp. This is due to the concentration of sweat glands that carry Dihydrotestosterone in these areas.

Women on the other hand generally thin in a diffuse manner.

Hair loss in men is often more dramatic, and follows a specific pattern of loss which has been termed "Male Pattern Baldness".

This loss is caused by Dihydrotestosterone (DHT).

DHT is the resulting product of direct contact between the enzyme 5-alpha-reductase found in the skin and scalp with the hormone testosterone.

DHT binds to receptor sites on the scalp and sends false signals to the functioning cells responsible for proper hair growth.

Nisim Shampoos and Stimulating Extracts have been clinically proven to safely and effectively neutralize both surface and dermal DHT.

Many of the hormonal changes women experience throughout their lives can result in hair loss. For example, some women lose hair after a pregnancy, during menopause or other hormonal imbalances.

Hormonal changes can cause hair loss by directly affecting the cells responsible for hair growth or by affecting the level of nutrients and blood flow to the follicle.

The hair follicle cannot maintain a healthy growth cycle without the proper nutrients. It may eventually fall out and die.

Other factors contributing to hair loss include:

• Poor blood circulation: Studies have shown that the blood flow to the scalp of men and women suffering from hair loss was significantly lower than in those not experiencing hair loss.

• Environmental pollutants: Further studies have indicated that pollutants in our atmosphere have contributed to the production of "environmental hormones" which can also contribute to hair loss.

• Poor hygiene: If a clean scalp is not maintained sweat and excess sebum will clog the hair follicles.

How does Nisim NewHair Biofactors work?

The deep cleansing scalp shampoo removes unwanted oils, sweat, dirt and excess sebum, as well as neutralizing surface DHT. The stimulating extracts penetrate further into the scalp to reduce the amount of DHT.

Organic enzymes and essential amino acids help feed and nourish weak and thinning hair.

Is Nisim NewHair Biofactors safe?

Yes, the Nisim products have passed rigorous health and safety tests. All the actives in the formulas are herbal, organic ingredients.

There are NO harmful side effects.

Is NewHair Biofactors safe to use on colored, permed, or chemically treated hair?

Yes. It is necessary to follow all manufacturers' directions and procedures, allowing the proper amount of time between chemical treatment and shampoo/extract application.

Will the shampoo help control hair loss due to menopause or after childbirth?

Yes, the results to date are extremely positive in both cases.

The shampoo alone will help to bring the excessive hair loss under control. The stimulating extract will help to restore the lost hair.

Is NewHair Biofactors effective for Alopecia Areata sufferers?

Yes. Nisim products have been very effective in stimulating hair growth in the patchy areas caused by Alopecia Areata.

Is NewHair Biofactors effective for anyone undergoing chemotherapy treatments?

Although no study results are available, anecdotal results indicate very positive results in maintaining the hair for as long as possible and promoting an accelerated rate of regrowth for similar quality hair as was lost during chemotherapy treatment.

How does NewHair Biofactors differ from competitive products?

• The shampoo can be used as a stand-alone product and is guaranteed to control excessive hair loss within one week.

• The product line is the most effective in the market with a clinically proven success rate of 85.7%.

• Nisim provides documentation as to the efficacy of the product and it's mode of action (how and why it works). Click here for a summary

• Nisim is the only non-pharmaceutical product that is clinically proven to neutralize DHT on the scalp.

Nisim NewHair Biofactors Usage Directions:

Shampoo

1. Wet your hair.

2. Apply shampoo and scrub scalp vigorously with your fingertips for one minute.

3. Rinse your hair thoroughly.

4. Repeat steps 2 and 3.

5. Do this daily.

Hair Stimulating Extract (Must be used only after Nisim Shampoo)

1. After shampooing, towel dry your hair.

2. Shake extract bottle well.

3. Apply extract (5-10 drops) to the area to be treated and massage into scalp with your fingertips (being careful not to rub).

4. Style hair as usual.

5. Later in the day apply extract only to the area to be treated and massage into scalp. (Note: If you have perspired heavily during the day, repeat shampoo before applying extract.)

6. Use extract twice each day.

Conditioner (Finishing Rinse or Oil Free)

1. After shampooing apply conditioner and massage thoroughly into the hair. Leave the conditioner for one minute.

2. Rinse hair thoroughly.

3. Apply Stimulating Extract.

Conditioner (Spray - Leave In)

1. To be used AFTER applying the Stimulating Extract.

2. Hold bottle eight inches from your hair and spray as required.

3. Style and set your hair as usual.

Note: It is not necessary to use one of Nisim's conditioners to achieve results. However, if you wish to use a conditioner it is recommended that Nisim conditioners be used to ensure there is no neutralizing effect to the actives in the shampoo or extract.

Customer Feedback

Here are some comments posted by users of NewHair Biofactors at BizRate, the consumer review site and on Nisim's user forum:

NewHair Biofactors Guarantee

NewHair Biofactors Ingredients List

NewHair Biofactors Clinical Study - Proof It Works!

Overview

Nisim International is a recognized industry leader in hair technology with over 20 years of research and product development.

Nisim's strength lies in its herbal extracts: the double extracted procedure used by its laboratories ensure that the extract will contain both water soluble components and the odd numbered (13, 15 and 21) carbon chains of essential fatty acids.

The extractable portion of the various herbs also contains complex polsaccharides along with other essential nutrients necessary to maintain and promote healthy hair regrowth.

NewHair Biofactors was clinically tested through a longitudinal study with 148 male participants with varying degrees of baldness.

First, the participants were photographed and initial hair counts were done in a 2.5 cm circular section of the balding area.

After five months of treatment with the herbal extract the same participants were once again photographed and hair counts were conducted on the same area as previously done.

The results of this test were exceptional, even out-performing Nisim's own expectations.

85.7% of the participants had an increase in their terminal hairs of 30% or greater and 40.8% of the study group had an increase of 100% or greater (ie. doubling, tripling, or more).

Nisim International has backed up its clinical results with in-depth biopsy studies that show the potential mode of action of the product.

A Clinical Study On A Natural Organic Extract Solution
For the Treatment Of Androgenic Alopecia
(A condensed version published in the Medical Post Vol.29 pp61. August 24, 1993)

Effect of Topical Application of an All Natural herbal Extract Solution
on Male Pattern Baldness

A. J. Farmilo. Ph.D.
M. A. Stratis. R.T.
H.L. Minuk. M.D.F.R.C.P.(C) A.B.I.M.

SUMMARY

One-hundred-and-forty-eight participants with varying degrees of male pattern baldness (androgenic alopecia) from Stage III to Stage VIII, participated in an open-ended study using an all natural compound solution to determine the effects of hair regrowth.

The participants were photographed and initial hair counts were done in a 2.5cm diameter area of their balding scalp.

After five months of treatment the participants were re-photographed and hair counts were done on the same 2.5cm diameter area of the scalp.

The results indicate that 85.7% of the men in the study had an increase in their terminal hairs of 30% or greater. When evaluating the percent increase more closely we find that we can break the data down into three separate groups:

1. Significant regrowth.

2. Moderate regrowth.

3. No change.

Showing a significant regrowth was 40.8% of the study group and had an increase of 100% or greater (doubling, tripling or more) of terminal hairs counted on their five month post-treatment photo as compared to their initial pre-treatment photo. Of this group the highest increase of hairs was 472%, the lowest increase was 102% with the mean at 193.7% increase of hairs.

The group of men showing moderate regrowth, which we classed as 30%-100% increase in terminal hair regrowth, was 44.9% of the study group. The mean increase of that group was 61.5% increase of hair regrowth.

The remainder of the group, classed no change, was 14.3% of the study group, with the range being minus 13% to +27% increase in hair counts with the mean at 6.7%.

The participants were also classed according to their degree of baldness usuing Hamilton's classification scheme. Class IV balding men showed the greatest percent increase at an overall average of 144% more terminal hairs than pre-treatment, with Classes V and VI both slightly less at approximately 120% average increase. Class VII and VIII responded the poorest at 102% and 65% average increases respectively.

Another factor considered was the amount of treatment used during the study. The participants were told to use at least one bottle per month (five bottles in five months) but were allowed to use more if desired. We did not see any significant advantage to using more than one bottle per month. Our conclusion is that the stimulartory effect of the compound is achieved at the use rate of one bottle per month.

The age range of the participants in the ability to regrow hair was not a factor. The range of the participants in this study was 24-68 years old, with the average age being 38.7 years.

In summary, this study concludes that the natural herbal extract solution has a stimulatory effect on hair growth for at least 8 out of 10 men with androgenic alopecia. The earlier stages of balding appear to respond to a higher degree, but significant improvement was seen in participants at all stages of baldness. There appears to be an optimum rate of use of the product, and age does not seem to be a factor in response. Further studies are being carried out to determine significant factors in the response to the treatment, and to analyze the mechanism of action of the compound.

ABSTRACT

Histological analysis of seven patients with male pattern baldness (androgenic alopecia) were assessed before and after treatment with a natural organic extract solution. Initial scalp biopsy specimens were obtained from an area of the balding scalp greather than 2.5cm in diameter.

Patients were provided with a scalp cleansing shampoo and the natural organic extract solution. They were instructed to cleanse the scalp daily and apply the extract at least twice daily. Fourteen weeks after the treatment the patients were re-biopsied from an area of the scalp adjacent to the initial biopsy and were evaluated.

Five of the seven patients demonstrated histological changes consistant with a significant increase in hair follicles at the cellular level, of their post treatment biopsies. Decreased levels of surface and epidermal scalp layer dihydrotestosterone (DHT) was also observed in the post treated biopsies using immuno-peroxidase techniques.

The monoclonal antibody QB-END-10 (CD 34) was also used immunohistochemically and demonstrated reactivity on the cell surface membrane of a portion of cells associated with the inner root sheath of the hair follicles of the post treatment biopsies. The reactivity of the QB-END-10 antibody raises many questions that require further investigation. Its significance is yet unkown, however the possibility that the natural organic extract may act as an endothelial derived relaxing factor (EDRF) and/or a stem cell stimulator cannot be ruled out.

REFERENCES

1. Familo A.J., Stratis M.A. and Minuk H.L.: Effect of a topical application of a natural organic extract on male pattern baldness: November 1992 (submitted for publication).

2. Cotsarelis G., Tung-Tien Sun, and Lavker R.M.: Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle and skin carcinogenesis; Cell, 1990:61;1329-1337.

3. Chase H.B.: Growth of hair: Physiol Rev; 1954;34;113-126.

4. Cotsarelis G., Cheng S.Z, Doug G., Sun T-T, and Lavker R.M: Existence of slow cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells; Cell, 1989:57;201-209.

5. Lavker R.M., and Sun T-T: Epidermal stem cells: J. Invest Dermatol, 1983:81;121s-127s.

6. Pinkus H: Epithelial-mesodermal interaction in normal hair growth, alopecia and neoplasis; J Dermatol, 1978:5;93-101.

7. Schermer A., Galvin S., and Sun T-T: Differentiation-related expression of a major 64K corneal keratin in vivo and in cell culture suggests limbal location of corneal epithelial stem cells: J Cell Biol, 1986:103;49-62.

8. Van Scott E.J., and Ekel T.M: Determinants of rate and kinetics of cell division in scalp hair: J. Invest Dermatol, 1963:41;269-273.

9. Wright N., and Allison M: The Biology of Epith Cell Populations; 1984 Vol 1: (Oxford, Clarendon Press).

10. Hamilton J.B: Male hormone stimulation is prerequisite and an incitant in common baldness: Am J Anat: 1942:71;451-454.

11. Anderson D.C: Sex hormone-binding globulin: J Clin Endocrinol, 1974:3;69-75.

12. Stewart M.E., Pachi P.E: Antiandrogens and the skin: Int J Dermatol, 1978:17;167-179.

13. Vermorken A.M., Goos C.A., and Roelofs H.J: A method for the evaluation of the local antiandrogenic action of 5-alpha reductase inhibitors on human skin: Br J Dermatol, 1980:102;695-71

14. Wood L., Carter D., Mills M., Hatzenbuehler N., and Vogeli G: Expression of calcylin, a calcium-binding protein, in the keratogenous region of growing hair: J Invest Dermatol, 1991:96,383-387.

15. Dardick I., Ostrynski V., Ekem J.K., and Lueng R: Immunohistochemical and ultrastructural correlates of muscle specific actin expression in pleomorphic ademonas and myoepitheliomas based on comparison of formalin and methanol fixation: Virch Arch Path, 1992:421;95-104.

16. DeLellis R.A. Diagnostic Immunohistochemistry: 1981 Vol 2 Masson Publishing.

17. Buhl A.E.: Minoxidil's action in hair follicles. J. Invest Dermatol: 1991; suppl: 73s-74s.

Reference: Effect of Topical Application of Nisim NewHair Biofactors, an All Natural herbal Extract Solution on Male Pattern Baldness

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